Research > Publications


Publication single view


Title: The relationships among heart rate variability, executive functions, and clinical variables in patients with panic disorder
Author(s): Anders Hovland, Ståle Pallesen, Åsa Hammar, Anita Lill Hansen, Julian F. Thayer, Mika P. Tarvainen and Inger Hilde Nordhus
Journal: International Journal of Psychophysiology
Year: 2012
Month: December
Volume: 86
Issue: 3
Pages: 269–275
DOI: 10.1016/j.ijpsycho.2012.10.004
File URL: vuams-pubs/Hovland_2012.pdf
Keywords: Panic disorder; Anxiety; Heart rate variability; Executive functions; Attention; Inhibition
Abstract: Heart rate variability (HRV) is reduced in patients who suffer from panic disorder (PD). Reduced HRV is related to hypoactivity in the prefrontal cortex (PFC), which negatively affects executive functioning. The present study assessed the relationships between vagally mediated HRV at baseline and measures of executive functioning in 36 patients with PD. Associations between these physiological and cognitive measures and panic-related variables were also investigated. HRV was measured using HF-power (ms2), and executive functions were assessed with the Wisconsin Card Sorting Test (WCST) and the Color-Word Interference Test (CWIT) from the Delis-Kaplan Executive Function System (D-KEFS). Panic-related variables comprised panic frequency, panic-related distress, and duration of PD. Performance on the neuropsychological measures correlated significantly with HRV. Both panic-related distress and duration of PD were inversely related with measures of HRV and cognitive inhibition. The current findings support the purported relationship between HRV and executive functions involving the PFC.

Back to the list view