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Title: A fluid response: Alpha-amylase reactions to acute laboratory stress are related to sample timing and saliva flow rate
Author(s): Tamás Nagy, Rene van Lien, Gonneke Willemsen, Gordon Proctor, Marieke Efting, Márta Fülöp, György Bárdos, Enno C.I. Veerman and JOS A. BOSCH
Journal: Biological Psychology
Year: 2015
Month: May
Day: 12
Volume: 109
Issue: 2015
Pages: 111-119
DOI: 10.1016/j.biopsycho.2015.04.012 0301-0511
File URL: vuams-pubs/Nagy_2015.pdf
Abstract: Salivary alpha-amylase (sAA) is used as a sympathetic (SNS) stress marker, though its release is likely codetermined by SNS and parasympathetic (PNS) activation. The SNS and PNS show asynchronous changes during acute stressors, and sAA responses may thus vary with sample timing. Thirty-four participants underwent an eight-minute memory task (MT) and cold pressor task (CPT). Cardiovascular SNS (pre-ejection period, blood pressure) and PNS (heart rate variability) activity were monitored continuously. Unstimulated saliva was collected repeatedly during and after each laboratory stressor, and sAA concentration (U/ml) and secretion (U/minute) determined. Both stressors increased anxiety. The MT caused an immediate and continued cardiac SNS activation, but sAAconcentrationincreasedattask cessationonly (+54%);i.e., whenthere was SNS–PNS co-activation. During the MT sAA secretion even decreased (-35%) in conjunction with flow rate and vagal tone. The CPT robustly increased blood pressure but not sAA. In summary, sAA fluctuations did not parallel changes in cardiac SNS activity or anxiety. sAA responses seem contingent on sample timing and flow rate, likely involving both SNS and PNS influences. Verification using other stressors and contexts seems warranted

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