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Title: Ambulatory measurement of the ECG T-wave amplitude
Author(s): Rene van Lien, Melanie Neijts, Gonneke Willemsen and ECO J. C. DE GEUS
Journal: Psychophysiology
Year: 2014
Month: August
Day: 13
DOI: 10.1111/psyp.12300
File URL: vuams-pubs/van_Lien_2014.pdf
Abstract: Ambulatory recording of the preejection period (PEP) can be used to measure changes in cardiac sympathetic nervous system (SNS) activity under naturalistic conditions. Here, we test the ECG T-wave amplitude (TWA) as an alternative measure, using 24-h ambulatory monitoring of PEP and TWA in a sample of 564 healthy adults. The TWA showed a decrease in response to mental stress and a monotonic decrease from nighttime sleep to daytime sitting and more physically active behaviors. Within-participant changes in TWA were correlated with changes in the PEP across the standardized stressors (r?=?.42) and the unstandardized naturalistic conditions (mean r?=?.35). Partialling out changes in heart rate and vagal effects attenuated these correlations, but they remained significant. Ambulatory TWA cannot replace PEP, but simultaneous recording of TWA and PEP provides a more comprehensive picture of changes in cardiac SNS activity in real-life settings.

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