||Mental stress can trigger myocardial infarction, with poor vascular responses to stress implicated as a pathway. Vascular
stress reactivity can be assessed by different methods, such as total peripheral resistance (TPR) and forearm blood ?ow
(FBF). Little is known about how these vascular assessments are linked. This was examined in two separate studies.
Healthy men (Study 1:N= 29, Study 2:N= 23) completed rest and mental arithmetic (Study 1: 8 min, Study 2: 16 min).
In both studies, heart rate, mean arterial pressure, and FBF increased in response to stress. In Study 1, no changes in TPR
were seen, but Study 2 found stress-induced increases in TPR. FBF was not linked to TPR at any time (all ps > .05). It
appears that limb vasculature and TPR responses to stress do not give the same information about impairments of the
vasculature. These ?ndings are relevant to the interpretation of prior research ?ndings and the design of future studies on
stress and vascular responses.